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KMID : 0614620150660050291
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Korean Journal of Gastroenterology
2015 Volume.66 No. 5 p.291 ~ p.296
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Primary Adenocarcinoma with Focal Choriocarcinomatous Differentiation in the Sigmoid Colon
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오숙경:Oh Sook-Kyoung
김형욱:Kim Hyung-Wook/강대환:Kang Dae-Hwan/최철웅:Choi Cheol-Woong/최유이:Choi Yu-Yi/임홍규:Lim Hong-Kyu/구자준:Goo Ja-Jun/최성열:Choi Sung-Yeol
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Abstract
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Primary colorectal choriocarcinoma is a rare neoplasm. Only 19 cases have been reported worldwide, most of which involved adenocarcinomas. The prognosis is usually poor, and the standard therapy for this tumor has not been established. A 61-year-old woman presented with constipation and lower abdominal discomfort. She was diagnosed with primary adenocarcinoma with focal choriocarcinomatous differentiation in the sigmoid colon and liver metastasis. Because the serum beta-human chorionic gonadotropin level was not significantly elevated, and because only focal choriocarcinomatous differentiation was diagnosed, we selected the chemotherapy regimen that is used for the treatment of metastatic colorectal adenocarcinoma. The patient survived for 13 months after the initial diagnosis. This is the first case in Korea to assess the suppressive effects of the standard chemotherapy for colorectal adenocarcinoma against coexisting colorectal choriocarcinoma and adenocarcinoma.
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KEYWORD
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Adenocarcinoma, Choriocarcinoma, Colon, Drug therapy
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